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Sequentially Formations of Csp 3 ‐Csp 2 and Csp 2 ‐Csp 2 Bonds by a One‐pot Reaction Involving N ‐Tosylhydrazone and p ‐Bromobenzeneboronic Acid
Author(s) -
He Jing,
Zhang Jie,
Dai Bin,
Liu Ping
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201900652
Subject(s) - chemistry , benzene , functional group , reagent , medicinal chemistry , organic chemistry , polymer
A one‐pot multi‐step reaction of two N ‐tosylhydrazones with p ‐bromobenzeneboronic acid was established. With the aid of sequentially formations of Csp 3 ‐Csp 2 bond and Csp 2 ‐Csp 2 bond, a series of 1‐benzyl‐4‐(1‐phenylvinyl)benzene derivatives can be synthesized from readily available starting materials in good yields. The transformation features a broad substrate scope and good functional group tolerance.