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A Chemodosimeter Exhibiting Fluorescence “Turn‐On” Response to Detect Copper(II) Ions: Cell Imaging and Logic Function
Author(s) -
Gupta Ramesh C.,
Dwivedi Sushil K.,
Razi Syed S.,
Singh Priya,
Koch Biplob,
Misra Arvind
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201900292
Subject(s) - fluorescence , copper , chemistry , ion , photochemistry , turn (biochemistry) , methylene , quantum yield , naked eye , fluorescence lifetime imaging microscopy , biophysics , optics , biochemistry , organic chemistry , physics , biology
In the present work the photophysical properties of a chemodosimeter, 2‐[4’‐( N,N’ ‐dimethylamino‐biphenyl)‐4‐methylene]‐iminophenol, 5 has been explored to recognize Cu 2+ ion selectively through naked eye sensitive fluorescence “turn‐on” response. The observed fluorescence enhancement (∼58 fold) and rise in quantum yield (34%) with rapid response time is attributed to the hydrolysis of aldimine function in the presence of copper. The cell imaging studies showed that chemodosimeter, 5 is well‐suited to detect Cu 2+ intracellularly. Additionally, the “Off–On” switching behavior of 5 has been utilized to mimic the function of a sequential logic circuit at molecular level.