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Access to Polyfluorinated Tetrahydropyranyl Amides via Prins‐Ritter Cyclization under Green Conditions
Author(s) -
Segovia Claire,
Fache Fabienne,
Pelotier Béatrice,
Piva Olivier
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201900110
Subject(s) - ritter reaction , chemistry , prins reaction , organic chemistry , solvent , catalysis
The formation of 4‐amido‐substituted tetrahydropyrans by Prins‐Ritter cyclisation under green solvent‐free conditions was investigated. The optimal conditions were applied to the synthesis of different tetrahydropyranyl amides, and subsequently to a new family of polyfluorinated derivatives when starting from hepta‐1,6‐dien‐4‐ol.