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Tin(II) triflate Catalysed Synthesis of 3‐Methyleneisoindolin‐1‐ones
Author(s) -
Sharma Simmi,
Nayal Onkar S.,
Sharma Arti,
Rana Rohit,
Maurya Sushil K.
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201804009
Subject(s) - trifluoromethanesulfonate , tin , functional group , chemistry , reaction conditions , combinatorial chemistry , catalysis , double bond , in situ , polymer chemistry , organic chemistry , polymer
We delineate a simple and straightforward tin(II) triflate catalyzed facile protocol for the synthesis of 3‐methyleneisoindolin‐1‐ones that applied to broad range of substrates, which simultaneously offers the functional group tolerance of the reaction and the stability of these scaffolds to the reaction conditions. In addition, in situ reduction of the exocyclic double bond in 3‐methyleneisoindolin‐1‐ones using PMHS is also reported.