Decorated Peptide Nanofibers with Cu Nanoparticles: An Efficient Catalyst for the Multicomponent Synthesis of Chromeno [2, 3‐ d ] pyrimidin‐8‐amines, Quinazolines and 2H‐ Indazoles

An efficient, simple and green protocol has been developed for the synthesis of 7, 10‐diaryl‐7Hbenzo [7, 8] chromeno[2,3‐ d ] pyrimidin‐8‐amine, 2H‐indazole and quinazoline derivatives in the presence of decorated peptide nanofibers with Cu nanoparticles. Peptide nanofibre has been synthesised by self ‐ assembly technique . In this work, the effect of succinic anhydride was evaluated in two conditions: i) without adding succinic anhydride at pH 4, ii) by adding succinic anhydride at pH 5. Synthesized peptide nanofiber was characterized by 1 H, 13 C, DEPT NMR spectroscopies (Distortionless enhancement by polarization transfer), CHNSO, scanning electron microscopy (SEM), fluorescence spectroscopy, UV/Vis, FTIR and transmission electron microscopy (TEM).