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A Novel One‐Pot Three‐Component Reaction for Rapid Access of Arylidene 2‐Aminoimidazolone Derivatives
Author(s) -
Hanif Aansa,
Sardar Aniqa,
Alazmi Meshari,
Tariq Haniya,
Emwas AbdulHamid,
Gao Xin,
Chotana Ghayoor Abbas,
Zaib Saleem Rahman Shah
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201803409
Subject(s) - chemistry , combinatorial chemistry , flexibility (engineering) , component (thermodynamics) , reaction conditions , simple (philosophy) , organic chemistry , mathematics , catalysis , physics , philosophy , statistics , epistemology , thermodynamics
A simple and convenient one‐pot reaction for the synthesis of arylidene 2‐aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2‐(methylthio)‐1 H ‐imidazol‐4(5 H )‐one is described. The reaction offers flexibility of use of electron‐rich and electron‐deficient benzaldehydes and mono and di‐substituted amines for the rapid development of combinatorial library.