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Oxidation of 1‐Phenylethane‐1,2‐Diol to 2‐Hydroxy‐1‐Phenylethan‐1‐One Catalyzed by Gold Nanocrystals
Author(s) -
Zhang Fangwei,
Zhang Jiali,
Guo Shouwu
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201803142
Subject(s) - selectivity , diol , catalysis , chemistry , yield (engineering) , nanocrystal , aqueous solution , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , materials science , nanotechnology , metallurgy
We demonstrate here that under a mild condition (aqueous solution, pH 7, 50 °C, 6 MPa O 2 ) gold nanocrystals (AuNCs) can catalyze the oxidation of 1‐phenylethane‐1,2‐diol to 2‐hydroxy‐1‐phenylethan‐1‐one selectively. And the yield can reach 87% when 94% the reactant is converted. Through comparing with different substrates, we show that the high selectivity of the AuNCs for 2‐hydroxy‐1‐phenylethan‐1‐one is due to the activity difference between the two hydroxy groups in the diol. AuNCs tend to catalyze the oxidation of the hydroxy group that locates in α‐C position of benzyl diol.