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Palladium‐Catalyzed Regioselective C‐H Bond ortho ‐Acetylation and Oxidative Homocoupling of N ‐Arylcarbamates
Author(s) -
Dabiri Minoo,
Osmani Chiman,
Nikbakht Roonak,
Movahed Siyavash Kazemi
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201803053
Subject(s) - regioselectivity , chemistry , catalysis , oxidative phosphorylation , acetylation , palladium , medicinal chemistry , surface modification , combinatorial chemistry , organic chemistry , biochemistry , gene
An efficient and straightforward protocol for the regioselective acyloxylation of N ‐arylarbamates via Pd‐catalyzed C−H bond functionalization has been demonstrated. The aliphatic and benzoic acid derivatives were used as the acyloxyl source to convert aromatic sp 2 C−H bonds into C−O bonds. Additionally, the oxidative homocoupling of N ‐arylarbamates were evaluated and gave the corresponding homocoupled products in good yields.