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Aerobic Oxidation of Methyl‐substituted β ‐Carbolines Catalyzed by N‐Hydroxyphthalimide and Metal Catalyst
Author(s) -
Qiu Hongda,
Liang Weida,
Zhang Gongjun,
Lin Miaoman,
Liu Wanmin,
Gao Zhanghua,
Wei Wenting,
Tang Chunlan,
Jin Haixiao,
Liang Hongze,
Yan Xiaojun
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201803007
Subject(s) - oxidizing agent , catalysis , chemistry , selectivity , molecular oxygen , salt (chemistry) , metal , transition metal , oxygen , organic chemistry , combinatorial chemistry
Carboxylic functionalized β ‐carbolines were successfully synthesized in good to excellent yields and high selectivity under mild conditions by aerobic oxidation in the presence of NHPI and transition metal salt using molecular oxygen as an oxidizing agent. A variety of derivatives of fascaplysin thus are available for structure‐bioactivity investigations.