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Decarboxylative Coupling of Cyclic α‐Amino Acid with Aldehyde and Kojic Acid: Direct Access to 2‐Pyrrolidinyl and 2‐Piperidinyl Kojic Acid Derivatives
Author(s) -
Krishna Rao Medikonda V.,
Reddy K. Nagarjuna,
Sridhar B.,
Subba Reddy B. V.
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802883
Subject(s) - kojic acid , aldehyde , chemistry , organic chemistry , catalysis , enzyme , tyrosinase
A novel class of kojic acid derivatives have been synthesized by a three component decarboxylative coupling of amino acid, aldehyde and kojic acid under thermal conditions. It is an entirely new strategy for the synthesis of 2‐pyrrolidinyl and 2‐piperidinyl kojic acid derivatives.