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2‐Hydroxyethyl‐Substituted (NHC)Pd(II)PPh 3 Complexes: Synthesis, Characterization, Crystal Structure and Its Application on Sonogashira Cross‐Coupling Reactions in Aqueous Media
Author(s) -
Aktaş Aydın,
Celepci Duygu Barut,
Gök Yetkin,
Aygün Muhittin
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802519
Subject(s) - sonogashira coupling , carbene , chemistry , triphenylphosphine , pyridine , ligand (biochemistry) , coupling reaction , palladium , crystal structure , organometallic chemistry , medicinal chemistry , nuclear magnetic resonance spectroscopy , aqueous solution , catalysis , stereochemistry , polymer chemistry , crystallography , organic chemistry , biochemistry , receptor
This study contains the synthesis of the novel series of the 2‐ hydroxyethyl substituted Pd‐based N‐heterocyclic carbene (NHC) / triphenylphosphine (PPh 3 ) complexes. The (NHC)Pd(II)PPh 3 complexes have been prepared from the PPh 3 ligand, replaced by 3‐chloro pyridine ligand in (NHC)Pd(II)(3‐Cl‐pyridine) complexes. The novel 2‐hydroxyethyl substituted (NHC)Pd(II)PPh 3 complexes have been characterized by using 1 H NMR, 13 C { 1 H}NMR, 31 P { 1 H}NMR, FTIR spectroscopy, and elemental analysis techniques. Molecular and crystal structure of 1 f was obtained by using single‐crystal X‐ray diffraction method. The novel 2‐hydroxyethyl substituted (NHC)Pd(II)PPh 3 complexes have been examined as catalysts in the Sonogashira cross‐coupling reactions aqueous medium and demonstrated excellent activity in this reaction.