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Zn(ClO 4 ) 2 ⋅6H 2 O‐Catalyzed One‐Pot Synthesis of Amides via Ritter Reaction with Alcohols, Acetic Anhydride and Nitriles
Author(s) -
Feng Chengliang,
Yan Bin,
Yao Wenjin,
Chen Junqing,
Ji Min
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802386
Subject(s) - acetic anhydride , ritter reaction , chemistry , catalysis , organic chemistry , solvent
The first example of the direct conversion of alcohols, acetic anhydride and nitriles into their corresponding amides through an ester reaction and Ritter reaction sequence is described. One‐pot reaction of alcohols, acetic anhydride and nitriles was catalyzed by Zn(ClO 4 ) 2 ⋅6H 2 O to afford corresponding amides in good to excellent yields for most case under solvent‐free conditions.