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A Smart and Efficient One‐Pot Green Synthesis of Novel 1, 2, 3‐Triazolyl Pyrazoline‐/Indazolyl‐Carbothioamide Hybrids under Solvent‐Free Grinding Strategy at Room Temperature
Author(s) -
Ranganathan Raja,
Archana Sivasubramaniyan,
Dinesh Murugan,
Jaabil George,
Nagarajan Sangaraiah,
Ponnuswamy Alagusundaram,
Saranya Kanagarajan,
Murugavel Saminathan
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802346
Subject(s) - pyrazoline , grinding , solvent , chemistry , combinatorial chemistry , organic chemistry , materials science , composite material
A smart and straightforward route has been developed for the green synthesis of novel 1,2,3‐triazolyl pyrazoline‐/indazolyl‐carbothioamide hybrids from easily accessible starting materials for the first time via one‐pot sequential four component reaction under solvent‐free grinding protocol at room temperature. Notably, this protocol is meritorious in the sense that it is inexpensive, expeditious, devoid of tedious separation methods, environmentally benign and it involves mild reaction conditions affording good to excellent yields (84‐97%) of the products.