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A Nontoxic, Bio‐friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System
Author(s) -
Sain Dibyendu,
Manna Abhishek,
Kumari Chanda,
Das Mukhopadhyay Chitrangada,
Goswami Shyamaprosad
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802315
Subject(s) - hypochlorite , hydrazide , chemistry , fluorescence , rhodamine b , hypochlorous acid , environmentally friendly , rhodamine , nuclear chemistry , combinatorial chemistry , organic chemistry , ecology , physics , quantum mechanics , photocatalysis , biology , catalysis
A simple, nontoxic, bio‐friendly, fluorescent chemodosimeter based on 2,4‐dinitrobenzene and thio‐rhodamine was designed and synthesized for the detection of toxic hypochlorite with high selectivity and sensitivity. First time, the oxidation property of the hypochlorite ion was applied on a hydrazide system (Ar−NH−N<). Practical utility of the sensor was proved through simple and fast visual detection of hypochlorite. Absorption and emission spectra exhibited the fast sensing capability of the sensor towards hypochlorite. The nontoxic, bio‐friendly properties of the sensor in living cells increased its real time practical applicability as it was successfully applied for in‐vitro detection of toxic hypochlorite in living cells.