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Hollow Organosilica Nanoparticles for Drug Delivery
Author(s) -
Rahmani Saher,
Akrout Alia,
Budimir Jelena,
Aggad Dina,
Daurat Morgane,
Godefroy Anastasia,
Nguyen Christophe,
Largot Hanene,
GaryBobo Magali,
Raehm Laurence,
Durand JeanOlivier,
Charnay Clarence
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201802107
Subject(s) - nanoparticle , drug delivery , materials science , microemulsion , nanotechnology , gemcitabine , chemical engineering , cancer , medicine , pulmonary surfactant , engineering
The sol‐gel synthesis of hollow organosilica nanoparticles incorporating amino groups with uniform size are described. These nanoparticles were successfully prepared via a microemulsion method. Then, the hollow nanoparticles were loaded with gemcitabine hydrochloride or methotrexate and studied in MCF‐7 breast cancer cells.