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I 2 /K 2 S 2 O 8 : An Unprecedented Deoxygenating System for N‐Oxides and Sulfoxides
Author(s) -
Raghuvanshi Dushyant Singh,
Verma Narsingh,
Gupta Atul
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201801838
Subject(s) - deoxygenation , reagent , quinoline , aryl , chemistry , oxide , pyridine , metal , amine gas treating , medicinal chemistry , inorganic chemistry , organic chemistry , catalysis , alkyl
A novel and efficient metal‐free approach has been disclosed for the deoxygenation of amine N‐oxides to amines and sulfoxides to corresponding sulfides using the green and economical reagent I 2 /K 2 S 2 O 8 . Deoxygenation of pyridine N‐oxide, quinoline N‐oxide, N , N ‐dialkylaniline N‐oxides, trialkylamine N‐oxides and aryl sulfoxides have been achieved in excellent yields. This method has been proven to be applicable to a wide range of substrates. A broad range of functional groups were well tolerated in this reaction system.