Premium
Transition‐Metal‐Free Hypervalent Iodine(III) Reagent‐Promoted Site‐Selective Solid‐Phase Synthesis of Mononitroarylamines
Author(s) -
An Delie,
Song Wenkang,
Peng Zhihong,
Zhang Yingjun,
Dong Wanrong
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201801783
Subject(s) - hypervalent molecule , reagent , electron paramagnetic resonance , chemistry , iodine , transition metal , catalysis , sodium nitrite , inorganic chemistry , organic chemistry , nuclear magnetic resonance , physics
A practical synthesis of nitroarylamines from protected arylamines and sodium nitrite was herein achieved in the presence of a hypervalent iodine(III) reagent without any transition metal‐catalysts and solvents. The site‐selective solid‐phase protocol took place in mortar at room temperature for short time through the free radical mechanism, as proved by electron paramagnetic resonance (EPR) analysis.