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1,10‐Phenanthroline‐Based Molten Salt as a Bifunctional Sulfonic Acid Catalyst: Application to the Synthesis of N ‐Heterocycle Compounds via Anomeric Based Oxidation
Author(s) -
Babaee Saeed,
Zolfigol Mohammad Ali,
Zarei Mahmoud,
Zamanian Javad
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201801476
Subject(s) - bifunctional , catalysis , salt (chemistry) , chemistry , anomer , molten salt , sulfonic acid , condensation , organic chemistry , combinatorial chemistry , phenanthroline , inorganic chemistry , physics , thermodynamics
1,10‐phenanthroline‐based molten salt as a bifunctional sulfonic acid [Phen(SO 3 H) 2 ]Cl 2 was designed and synthesized. The described nano molten salt has two SO 3 H acid groups and a rigid structure that allows the rotation of the molecule to have a unique catalytic ability. This catalyst was applied for the synthesis of N ‐heterocyclic compounds such as quinazolines, quinazolinones, acridines and dihydropyridines via multi‐component condensation reactions. These compounds are highly regarded for their medicinal and biological properties. The effect of different functional groups at the corresponding products for developing the new mechanisem entitled “anomeric based oxidation” (ABO) were studied. The major advantages of the presented methodology are mild conditions, high efficiency, short reaction times and reusability of the catalyst.