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Nonanebis (peroxoic acid)‐Mediated Transition‐Metal‐Free Approach for N‐Oxide Synthesis
Author(s) -
Gayakwad Eknath M.,
Patel Khushbu P.,
Shankarling Ganapati S.
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800972
Subject(s) - oxide , catalysis , transition metal , metal , protocol (science) , chemistry , combinatorial chemistry , reaction conditions , materials science , organic chemistry , medicine , alternative medicine , pathology
An efficient, metal catalyst free approach for the synthesis of N‐oxide is described. Nonanebis (peroxoic acid) is used as a source of oxygen, it is non shock sensitive, stable and easy to handle at room temperature. This protocol is applicable for various aromatic as well as aliphatic tertiary amines in good to excellent yields. Less reaction time, optimum temperature, easy workup procedure and metal catalyst free approach is the beauty of the present protocol.