Premium
β ‐Lactam‐Synthon Interceded Diastereoselective Synthesis of 2‐Azido‐ γ ‐amino Alcohols with Subsequent Transformations to Functionally Enriched Heterocycles
Author(s) -
Singh Amandeep,
Sharma Bharvi,
Sachdeva Divya,
Mehra Vishu,
Singh Pardeep,
Kumar Vipan
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800512
Subject(s) - synthon , lactam , combinatorial chemistry , chemistry , protocol (science) , stereochemistry , organic chemistry , medicine , alternative medicine , pathology
The present manuscript explicates Boron‐dimethylsulfide‐promoted diastereoselective synthesis of 2‐azido‐γ‐amino alcohols using β ‐lactam synthon protocol along with its utilization in the formation of diversely functionalized heterocycles having biological relevance. The developed protocol has the potential to surpass the typical drawbacks of conventional protocols.