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A Ligand/Additive/Base‐Free C(sp 2 )‐H Activation and Isocyanide Insertion in PEG‐400: Synthesis of Indolizine/Imidazoline‐Fused Heterocycles
Author(s) -
Kumar K. Shiva,
Rajesham Bandari,
Kumar N. Praveen,
Ramulu Meesa Siddi,
Dandela Rambabu
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800397
Subject(s) - indolizine , imidazoline receptor , chemistry , isocyanide , ligand (biochemistry) , formamides , combinatorial chemistry , photochemistry , medicinal chemistry , stereochemistry , polymer chemistry , organic chemistry , catalysis , medicine , biochemistry , receptor
A ligand/base/metal oxidant free Pd‐catalyzed C(sp 2 )–H activation, followed by isocyanide insertion to synthesize indolizine/imidazoline fused heterocyclics in PEG‐400 as a recyclable solvent. The present transformation is greener and an efficient strategy using oxygen as external oxidant. The spectroscopic properties of selected indolizine/imidazoline fused heterocyclics were studied by UV−visible and fluorescence spectroscopy.