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Environmentally Benign Deep Eutectic Solvent for Synthesis of 1,3‐Thiazolidin‐4‐ones
Author(s) -
Yedage Dattatray B.,
Patil Dattatray V.
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800157
Subject(s) - yield (engineering) , deep eutectic solvent , eutectic system , environmentally friendly , solvent , catalysis , chemistry , organic chemistry , reaction conditions , combinatorial chemistry , materials science , metallurgy , ecology , alloy , biology
This paper explores the versatility and effectiveness of Deep Eutectic Solvent (DES) as an efficient catalyst cum reaction media for the preparation of biologically important 1,3‐ thiazolidin‐4‐one derivatives. This methodology was objected to overcome the limitations of the previously reported methods such as the use of expensive and toxic solvents, long reaction time and low yield. This protocol is rapid, environmentally benign, with good to high yield of products. The DES media could be reused up to five times without any appreciable decrease in the yield.