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Microwave Accelerated Synthesis of 2‐Amino‐4 H ‐Chromenes Catalyzed by WELFSA: A Green Protocol
Author(s) -
Kantharaju Kamanna.,
Khatavi Santosh. Y.
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800096
Subject(s) - malononitrile , catalysis , yield (engineering) , aldehyde , resorcinol , chemistry , one pot synthesis , mass spectrometry , organic chemistry , condensation , condensation reaction , proton nmr , nuclear chemistry , chromatography , materials science , physics , metallurgy , thermodynamics
In this work, agro‐waste stuff was employed as a natural source catalyst for the synthesis of 2‐amino‐4H‐chromene as green protocol. The synthesis was carried out in three component one‐pot condensation of aldehyde, malononitrile and naphthol/resorcinol in the presence of Water Extract of Lemon Fruit Shell Ash (WELFSA ) as a greener catalyst. Different synthetic methods were examined for the synthesis of 2‐amino‐4H‐chromene under WELFSA extract, and found microwave assisted reaction gave faster reaction rate with the separation of solid in high yield. The isolated products were checked for its purity by TLC. The final product was characterized by FT‐IR, 1 H‐, 13 C‐NMR and mass spectrometry.