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Open Flask, Clean and Practical Protocol for Diastereoselective Syntheses of Oxindole Containing Phosphinoyl Compounds under Catalyst‐Free and Solvent‐Free Conditions
Author(s) -
Bai Rekha,
Choudhary Rakhee,
Singh Pratibha,
Thakuria Ranjit,
Sharma Mahesh C.,
Badsara Satpal Singh
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201800009
Subject(s) - oxindole , catalysis , chemistry , organic chemistry , solvent , combinatorial chemistry
An open flask, practical C−P bond formation between oxindole containing allyl alcohols and phosphorous surrogates under catalyst‐free and solvent‐free conditions is described. The C−P bond formation is completely diastereoselective and amenable to a variety of multifunctional allyl alcohols under the reaction conditions employed, providing the desired products in excellent yields.