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Cover Picture: Pot, Atom, Step Economic (PASE) Approach towards ( Aza )‐2,2′‐Bipyridines: Synthesis and Photophysical Studies (ChemistrySelect 02/2018)
Author(s) -
Khasanov Albert F.,
Kopchuk Dmitry S.,
Kim Grigory A.,
Slepukhin Pavel A.,
Kovalev Igor S.,
Santra Sougata,
Zyryanov Grigory V.,
Majee Adinath,
Chupakhin Oleg N.,
Charushin Valery N.
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201703123
Subject(s) - hydrazine (antidepressant) , hydrazone , chemistry , cover (algebra) , triazine , condensation , combinatorial chemistry , atom (system on chip) , chelation , condensation reaction , medicinal chemistry , polymer chemistry , organic chemistry , catalysis , physics , computer science , mechanical engineering , chromatography , engineering , thermodynamics , embedded system
The cover picture shows a pot‐, atom‐, and step‐economic (PASE) approach towards α‐unsubstituted ( aza )‐2,2'‐bipyridines, as well as their 3,6‐disubstituted‐1,2,4‐triazine precursors. ( Aza )‐2,2'‐bipyridines, such are of special interest due to their biological activities and metal cation chelating properties. Precursors 1,2,4‐triazines were obtained by the heterocyclization of in situ generated iminoesters (from heteroarylnitriles) with readily available iso nitrosoacetophenone hydrazone. The condensation of the corresponding nitriles with iso‐ nitrosoacetophenone hydrazine and followed by aza‐ Diels‐Alder reaction with the appropriate dienophile afforded the corresponding bipyridines. More information can be found in the Full Paper by Khasanov et al . (DOI: 10.1002/slct.201702350). The cover picture was created by Dr. Sougata Santra.