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Ascorbic Acid as a Highly Efficient Organocatalyst for ipso ‐Hydroxylation of Arylboronic Acid
Author(s) -
Das Sameeran Kumar,
Bhattacharjee Prantika,
Bora Utpal
Publication year - 2018
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201703036
Subject(s) - ascorbic acid , hydroxylation , chemistry , yield (engineering) , catalysis , combinatorial chemistry , aqueous solution , organic chemistry , enzyme , food science , materials science , metallurgy
An effective organocatalyst, ascorbic acid has been successfully applied for the ipso ‐hydroxylation of arylboronic acid using 30% aqueous H 2 O 2 as oxidant in water at ambient temperature. The methodology proceeds without using any metal catalyst or base and avoids harsh reaction conditions. The protocol is applicable to various electronically diverse arylboronic acid moieties with good to excellent yield.