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PTSA . H 2 O‐Catalyzed Reaction of 3‐Aminocoumarins and Phenylacetaldehydes: A Route to Access Various Pyrido(2,3‐ c )coumarin Derivatives
Author(s) -
Belal Md.,
Khan Abu T.
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201702300
Subject(s) - coumarin , catalysis , pyridine , acetonitrile , chemistry , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
A number of pyrido(2, 3‐ c )coumarin derivatives were accomplished from various 3‐aminocoumarins and phenylacetaldehydes in acetonitrile using 10 mol% p ‐toluenesulfonic acid monohydrate (PTSA . H 2 O) as a catalyst. The protocol is an easy approach to synthesize a number of biologically important coumarin fused pyridine derivatives.