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Halogen‐Induced Friedel‐Crafts Alkenylation Reactions with Haloalkynes: Direct Access to gem ‐1, 1‐Dihaloalkenes
Author(s) -
Maji Biswajit,
Bhattacharya Aditya,
Hazra Sunit
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201702265
Subject(s) - friedel–crafts reaction , intramolecular force , aryl , halogen , chemistry , organic chemistry , combinatorial chemistry , catalysis , alkyl
A simple and efficient tactic for the synthesis of gem ‐hetero‐ or homo‐dihaloalkenes is reported from haloalkynes where Friedel‐Crafts alkenylation is a key step. The method provides functionalized tetrasubstituted alkenes which are important precursors in organic synthesis. The strategy is further extended with intramolecular Friedel‐Crafts alkenylation on ω ‐aryl alkynes to produce annulated arene carbocycles in a simple manner.