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Gold Nanoparticles from Vegetable Extracts Using Different Plants from the Market: A Study on Stability, Shape and Toxicity
Author(s) -
Clemente Ilaria,
Ristori Sandra,
Pierucci Federica,
MunizMiranda Maurizio,
Salvatici Maria Cristina,
Giordano Cristiana,
Meacci Elisabetta,
Feis Alessandro,
Gonnelli Cristina
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201701681
Subject(s) - nanoparticle , colloidal gold , nanotechnology , materials science , transmission electron microscopy , drug delivery , chemical engineering , stromal cell , chemistry , engineering , medicine , pathology
The use of nanoparticles for many advanced applications (drug‐delivery, biosensors, catalysts etc.) involves their large scale production. This engenders the need of synthetic methods and reactants which are sustainable as well as safe. Natural products allow to prepare nanoparticles via eco‐friendly processes, which is especially true for reducing/capping agents obtained from agricultural by‐products. Here, we prepared gold nanoparticles (AuNPs) in high yields by using extracts from the leaves of marketable plants and by following different synthetic routes (i. e. one‐ or two‐steps). The size and morphology of the obtained AuNPs were determined by Transmission Electron Microscopy (TEM), while surface coverage with different chemical species was investigated by surface‐enhanced Raman scattering (SERS). In vitro experiments on bone‐marrow mesenchymal stromal cells (MSCs) were used to study the effect on cell viability, as a first step toward toxicity assessment. This work allowed to select the nanoparticles with highest SERS activity at infrared excitation wavelength, in view of their possible use as shelf products.