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Molecular Iodine‐Mediated Ring Opening Reaction of Spiro‐Epoxy Oxindoles with Electron Rich Arenes
Author(s) -
Shanker Medi,
Venkanna Avudoddi,
Prasad Pulaganti Vijaya,
Swamy Marapala Kumara,
Venkateswar Rao Pallapothula
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201701561
Subject(s) - epoxy , iodine , ring (chemistry) , chemistry , reaction conditions , organic chemistry , combinatorial chemistry , catalysis
Highly efficient and facile methodology has been developed for the ring opening reaction of spiro‐epoxy oxindoles with electron rich arenes in presence of molecular iodine. These reactions can be carried out easily under mild reaction conditions to afford functionalized 2‐indolinone derivatives in excellent yields.