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A New Chirally Organized Trifluoromethylanthrylmethanol Derivative and Its Application as Chiral Solvating Agent
Author(s) -
Monteagudo Eva,
de March Pedro,
ÁlvarezLarena Ángel,
Virgili Albert
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201701429
Subject(s) - enantiomer , chirality (physics) , anthracene , chemistry , stoichiometry , derivative (finance) , methylene , combinatorial chemistry , stereochemistry , organic chemistry , medicinal chemistry , chiral symmetry , physics , quantum mechanics , financial economics , nambu–jona lasinio model , economics , quark
The synthesis and structure of 1,1′‐(((10,10’‐(1,1′‐binaphthalene)‐2,2′‐diylbis(oxy))bis(methylene))bis(anthracene‐10,9‐diyl))bis(2,2,2‐trifluoroethanol), 4 , is reported. This compound owns both axial and central chirality allowing its use as a chiral solvating agent (CSA) for the enantiomeric composition determination of several mixtures of chiral aromatic alcohols and amines using NMR. The study of the resulting diastereoisomeric complexes was carried out by determining its stoichiometry and association binding constants.