Premium
Bipyridine Facilitates Regioselective Dimerization of Alkynes in the Absence of Transition Metal
Author(s) -
Midya Ganesh Chandra,
Parasar Bibudha,
Maiti Subhadip,
Dash Jyotirmayee
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201701091
Subject(s) - regioselectivity , catalysis , chemistry , transition metal , selectivity , aryl , bipyridine , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , alkyl , crystal structure
We herein present a transition metal free protocol for the dimerization of terminal aryl alkynes to prepare enyne derivatives using potassium tert ‐butoxide in the presence of catalytic amount of 2,2′‐bipyridine. The reaction is compatible with a wide range of substrates resulting in high to moderate yields of the corresponding head‐to‐head dimers with E ‐selectivity.