Catalyst‐Free Synthesis for Pyrazole‐Fused Isocoumarins in Recyclable and Biodegradable Reaction Medium | Zendy

Yadav Vijay B. | Zendy; Rai Pragati | Zendy; Sagir Hozeyfa | Zendy; Kumar Akhilesh | Zendy; Siddiqui Ibadur R. | Zendy

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Catalyst‐Free Synthesis for Pyrazole‐Fused Isocoumarins in Recyclable and Biodegradable Reaction Medium

Author(s) -

Yadav Vijay B.,

Rai Pragati,

Sagir Hozeyfa,

Kumar Akhilesh,

Siddiqui Ibadur R.

Publication year - 2017

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201700976

Subject(s) - isocoumarins , pyrazole , simplicity , combinatorial chemistry , chemistry , ninhydrin , catalysis , biochemical engineering , computer science , organic chemistry , engineering , biochemistry , philosophy , epistemology , amino acid

An efficient and facile protocol for the synthesis of pyrazole‐fused isocoumarins via reactions of readily available ninhydrin and arylhydrazone is disclosed. This approach illustrate operational simplicity, offering a modified and expedient methodology for the direct construction of synthetically useful pyrazole‐fused isocoumarins compounds in good to excellent yields. This documented strategy, provide a cost effective and environmentally benign alternative to the other existing method.

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