Copper(I)‐Catalyzed Regioselective C‐H Amination of  N ‐Pyridyl Imines Using Azidotrimethylsilane and TBHP: A One‐Pot, Domino Approach to Substituted Imidazo[4, 5‐b]pyridines | Zendy

Bhargava Gaurav | Zendy; Kumar Yogesh | Zendy

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Copper(I)‐Catalyzed Regioselective C‐H Amination of N ‐Pyridyl Imines Using Azidotrimethylsilane and TBHP: A One‐Pot, Domino Approach to Substituted Imidazo[4, 5‐b]pyridines

Author(s) -

Bhargava Gaurav,

Kumar Yogesh

Publication year - 2017

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201700969

Subject(s) - amination , domino , chemistry , imine , regioselectivity , catalysis , copper , substrate (aquarium) , cascade reaction , azide , functional group , combinatorial chemistry , one pot synthesis , medicinal chemistry , organic chemistry , oceanography , polymer , geology

A novel, efficient and one‐pot multicomponent copper‐catalyzed amination of N ‐pyridyl imines is described. This, one‐pot, multicomponent reaction, in which imine acts as a directing group by chelating to the metal core, affords a domino approach for the transformation of the commercial pyridinamines, aldehydes and azide into valuable imidazo[4, 5‐b]pyridines with wide substrate extent and diversity.

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