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Palladium‐Catalyzed Selective Mono‐Chlorination of o ‐Carboranes: Changing the Concept of FeCl 3 from Lewis Acid to Chlorine Source in Carboranes
Author(s) -
Xu TaoTao,
Zhang CaiYan,
Cao Ke,
Wu Ji,
Jiang Linhai,
Li Jing,
Li Bo,
Yang Junxiao
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700704
Subject(s) - chemistry , catalysis , palladium , chlorine , electrophile , selectivity , lewis acids and bases , catalytic cycle , medicinal chemistry , electrophilic addition , organic chemistry
A palladium catalyzed selective mono‐chlorination of o ‐carboranes has been developed by utilization the oxidizability of FeCl 3 , and a series of mono‐chlorinated o ‐carboranes with active groups have been synthesized with moderate to good yields as well as good selectivity. A plausible mechanism involving the electrophilic palladation of B‐H bond and the Pd(II)/Pd(IV) catalytic cycle was proposed.
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