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Pd@TTF Tailored Nanostructured Platform: Voltammetric Estimation of Ceftazidime
Author(s) -
Tiwari Preeti,
Azad Uday Pratap,
Gupta Sandeep,
Prakash Rajiv
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700700
Subject(s) - materials science , palladium , electrochemistry , tetrathiafulvalene , nanocomposite , detection limit , molecule , combinatorial chemistry , chemical engineering , nanotechnology , chemistry , electrode , catalysis , organic chemistry , chromatography , engineering
Herein, we report the synthesis of tetrathiafulvalene stabilized palladium nanocomposite (Pd@TTF) through one‐step simple chemical route without using any external reducing agent. Prepared Pd@TTF was further used for the electrochemical determination of ceftazidime (CFZ). A possible interaction mechanism has been proposed for the formation of palladium NPs sandwiched between TTF radical cations (Pd@TTF). As‐prepared Pd@TTF are characterized by using various techniques to investigate its structural, optical, and electrochemical properties The interaction of drug molecules with Pd@TTF is utilized in sensing of the drug using voltammetric techniques. The limit of detection (LOD) of CFZ is achieved up to 0.5 μM. The Pd@TTF modified sensor probe is successfully used for the determination of CFZ in the commercially available CFZ injection.