Premium
Design and Synthesis of BODIPY‐Cored Near IR‐emitting Lipophilic and Water‐Soluble Dendritic Platforms
Author(s) -
Ramesh Palakuri,
KarablineKuks Jeny,
WeissShtofman Mor,
Portnoy Moshe
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700377
Subject(s) - fluorophore , bodipy , moiety , fluorescence , dendrimer , solubility , chemistry , monomer , aqueous solution , photochemistry , molecule , combinatorial chemistry , organic chemistry , polymer , physics , quantum mechanics
Capitalizing on our experience in constructing branched and dendritic monomers with functionalizable aromatic moiety at the focal point and various terminal groups, we prepared lipophilic and water‐soluble dendrimers with BODIPY fluorophore in the core, emitting in the green and near IR spectral regions. The dendrimers, incorporating aliphatic tails, exhibited excellent fluorescence properties in apolar organic solvents, while those with the triethylenglycol‐based tails were highly fluorescent in polar organic solvents as well. The water solubility induced by the terminal hexaethyleneglycol tails enables fluorescence of the dyes also in aqueous media. The phenolic hydroxyls in the molecules enable attachment of linkers for prospective conjugation of additional units.