Premium
Silver‐Catalyzed Biomimetic Transfer Hydrogenation of N‐Heteroaromatics with Hantzsch Esters as NADH Analogues
Author(s) -
Pi Danwei,
Zhou Haifeng,
Cui Peng,
He Renke,
Sui Yuebo
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700327
Subject(s) - transfer hydrogenation , catalysis , yield (engineering) , chemistry , combinatorial chemistry , reaction conditions , organic chemistry , materials science , ruthenium , metallurgy
A silver‐catalyzed biomimetic transfer hydrogenation of N ‐heteroaromatics with Hantzsch esters as NADH analogues has been developed. The reaction proceeded smoothly under mild conditions to give the corresponding reductive products in up to 99% yield. The asymmetric version of this reaction was also conducted preliminarily with up to 66% ee.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom