Metal‐Free Regioselective Dual C‐H Functionalization in a Cascade Fashion: Access to Isocryptolepine Alkaloid Analogues | Zendy

Murugan Arumugavel | Zendy; Vidyacharan Shinde | Zendy; Ghosh Ruma | Zendy; Sharada Duddu S. | Zendy

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Metal‐Free Regioselective Dual C‐H Functionalization in a Cascade Fashion: Access to Isocryptolepine Alkaloid Analogues

Author(s) -

Murugan Arumugavel,

Vidyacharan Shinde,

Ghosh Ruma,

Sharada Duddu S.

Publication year - 2017

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201700263

Subject(s) - regioselectivity , surface modification , indazole , benzylamine , combinatorial chemistry , chemistry , cascade , cascade reaction , substrate (aquarium) , organic chemistry , catalysis , oceanography , chromatography , geology

A metal‐free regioselective approach to annulated indazoles is presented via dual C−H functionalization of indazole and benzylamine in a cascade fashion. The salient features of the present protocol are regioselective C3‐functionalization, one‐pot synthesis of annulated scaffolds, metal‐free, peroxide‐free, operationally simple and wide substrate scope.

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