Premium
Investigation of the Spectroscopic, Thermal and Electrochemical Properties of Tris‐(glycinato)chromium(III)
Author(s) -
Uddin Kabir M.,
Habib Ahsan Md.,
Henry David J.
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700079
Subject(s) - chromium , tris , electrochemistry , chemistry , inorganic chemistry , materials science , organic chemistry , biochemistry , electrode
The tris‐glycinatochromium(III) complex ([Cr(gly) 3 ]) has been proposed as a nutritional supplement and treatment for Type 2 diabetes. The exact mode of action of this and other Cr(III) supplements is not known but may involve redox reactions with biomolecules. In this study fac ‐[Cr(gly) 3 ] was synthesized and the electrochemical properties investigated by cyclic voltammetry. The complex undergoes a reversible one electron reduction with E 1/2 =−0.66 to −0.69 V that is essentially independent of scan rate. Thermal decomposition was explored by differential scanning calorimetry under nonisothermal conditions from 30−1000 °C. Structural parameters obtained from DFT calculations are in good agreement with crystallographic data. The reduced form of the complex has a high‐spin quintet electronic configuration due to the small crystal field splitting from the weak π‐donor ligands. Both the theoretical calculations and the electrochemical measurements demonstrate that the complex is stable in the anionic form. These results indicate that [Cr(gly) 3 ] can undergo reversible electron transfer, which may play a role in it's biological activity.