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The Synthesis of 3‐Arylquinolines from o ‐Nitrobenzaldehydes and β ‐Nitrostyrenes via an Iron‐Promoted Reductive Cyclization
Author(s) -
Li DengKui,
Cai Qun,
Zhou RongRong,
Wu YanDong,
Wu AnXin
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201700063
Subject(s) - chemistry , hydrolysis , quinoline , reductive elimination , reduction (mathematics) , medicinal chemistry , combinatorial chemistry , catalysis , organic chemistry , mathematics , geometry
An iron‐mediated one‐pot synthesis of 3‐arylquinolines from o ‐nitrobenzaldehydes and β ‐nitrostyrenes has been developed. Iron acted as dual roles to trigger the reduction of o ‐nitrobenzaldehydes and reduction hydrolysis of β ‐nitrostyrenes, which subsequently integrated to quinoline derivatives.