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Construction of Spiro[indeno[2,1‐ e ]pyrrolo[3,4‐ b ]pyridine‐10,3′‐indoline] and Indeno[1,2‐ b ]pyrrolo[3,4‐ e ]pyridine via Three‐Component Reaction
Author(s) -
Xiao Man,
Jiang YanHong,
Yan ChaoGuo
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201602042
Subject(s) - pyridine , chemistry , boron trifluoride , triethylamine , medicinal chemistry , methylene , indoline , component (thermodynamics) , ethanol , organic chemistry , catalysis , physics , thermodynamics
The three‐component reaction of β‐ enamino imides, isatins and indan‐1,3‐dione in refluxing ethanol in the presence of triethylamine afforded functionalized spiro[indeno[2,1‐ e ]pyrrolo[3,4‐ b ]pyridine‐10,3′‐indolines] in good yields. The similar three‐component reaction of β‐ enamino imides, aromatic aldehydes and indan‐1,3‐dione in methylene dichloride in the presence of boron trifluoride etherate resulted in the corresponding indeno[1,2‐ b ]pyrrolo[3,4‐ e ]pyridine derivatives.