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New 1,1’‐Ferrocene Bis(sulfonyl) Reagents
Author(s) -
Chanawanno Kullapa,
Holstrom Cole,
Nemykin Victor N.,
Herrick Richard S.,
Ziegler Christopher J.
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201601748
Subject(s) - sulfonyl , ferrocene , reagent , chemistry , organic chemistry , electrochemistry , alkyl , electrode
Several new 1,1’‐bis(sulfonyl)ferrocenes designed for the synthesis of sulfonamide linked biological conjugates have been prepared. 1,1’‐Bis(sulfonylbromide)ferrocene can be produced from the corresponding sulfonylchloride via a bis(sulfonylhydrazide) intermediate. Bis(sulfonyl‐ N ‐hydroxybenzotriazole)ferrocene can also be synthesized from the sulfonyl chloride, and reaction of glycine methyl ester with the sulfonyl chloride affords a [3]ferrocenophane complex. All new compounds have been structurally characterized by X‐ray crystallography.