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Cu(OAc) 2 /I 2 ‐Mediated Direct Sulfonylation of Benzo[d]imidazoles with Disulfides
Author(s) -
Wei Liang,
Deng JianChao,
Zhuo BaoLiu,
Xu Li,
Tang RiYuan
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201601601
Subject(s) - chemistry , iodine , oxygen atom , medicinal chemistry , oxygen , combinatorial chemistry , organic chemistry , molecule
A novel method for direct sulfonylation of disulfides with benzo[d]imidazoles mediated by Cu(OAc) 2 and iodine has been established. This protocol allows for the preparation of diverse sulfonamides with broad functionalities in moderate to good yields. The control experiments have shown that the oxygen atoms in sulfonamides come from water.