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Metal–free GO‐SiPr‐SO 3 H Nanosheets Catalyzed Ultrasound Promoted One–pot Synthesis of Star‐Shape Phenolic Compounds in Water and Study of Their In–vitro Antimicrobial Activities
Author(s) -
Golestanzadeh Mohsen,
Naeimi Hossein,
Zahraie Zohreh
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201601595
Subject(s) - catalysis , aldehyde , antimicrobial , in vitro , metal , chemistry , yield (engineering) , ultrasound , irradiation , nuclear chemistry , materials science , combinatorial chemistry , organic chemistry , biochemistry , metallurgy , medicine , physics , nuclear physics , radiology
An efficient and pseudo‐three‐component approach to obtain star‐shape phenolic compounds using 2,4‐dialkylphenol and aromatic, aliphatic, bis‐aldehyde and heteroaldehyde was reported using GO‐SiPr‐SO 3 H in water under ultrasound irradiation. The ultrasound irradiation had positive effect on catalytic activity of the GO‐SiPr‐SO 3 H catalyst. The desired products were achieved in good to excellent yields at short reaction times. Also, the structure of star‐shape phenolic compounds was approved using density functional theory (DFT) calculation. In addition, in vitro antimicrobial activity of the synthetic compounds was evaluated.