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Lipid Matrices Destabilization Induced by Some Newly Synthesized Pyridinium Salts
Author(s) -
Luchese Angélica M.,
Di Vitta Cláudio,
Marzorati Liliana,
Yamaoka Patrícia,
Funari Sérgio S.
Publication year - 2017
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201601588
Subject(s) - pyridinium , salt (chemistry) , popc , chemistry , matrix (chemical analysis) , molar ratio , pyridinium compounds , inorganic chemistry , crystallography , organic chemistry , chromatography , lipid bilayer , biochemistry , membrane , catalysis
The influence of some newly synthesized pyridinium salts on the structural behavior of two lipid matrices formed with POPC or POPE was investigated by using SAXD. The structural impact / evolution of temperature scans were determined on samples prepared with different pyridinium salts / lipid helper molar ratio compositions, in water. In POPC based samples most complexes showed a strong sensitivity to the presence of pyridinium salts, mostly destructive of the long range order. A clear dependence of the structural behavior was correlated with pyridinium salt concentration. In POPE based samples the conformation of the hydrophobic part of such pyridinium salts seems to have a significant impact on the overall matrix structural behavior.