N‐Bromosuccinimide Promoted Direct Thiolation of Imidazoheteroaryl C‐H bonds with Disulfides | Zendy

Maddi Raghavender Reddy | Zendy; Shirsat Prashishkumar K. | Zendy; Kumar Santosh | Zendy; Meshram H. M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

N‐Bromosuccinimide Promoted Direct Thiolation of Imidazoheteroaryl C‐H bonds with Disulfides

Author(s) -

Maddi Raghavender Reddy,

Shirsat Prashishkumar K.,

Kumar Santosh,

Meshram H. M.

Publication year - 2017

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201601460

Subject(s) - regioselectivity , chemistry , n bromosuccinimide , combinatorial chemistry , base (topology) , medicinal chemistry , organic chemistry , halogenation , catalysis , mathematics , mathematical analysis

A one‐pot protocol has been demonstrated for the regioselective sulfenylation of imidazoheterocycles with disulfides. In this method, thiols are converted to sulfenyl bromides and reacted with 2‐phenylimidazo [1, 2‐a] pyridines. This simple procedure is highly capable for sulfenylation with readily available starting materials in good to excellent yields under transition metal and base free conditions.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research