Synthesis, Chemistry and Structure of Some 1,1‐Dimethylcyclopropazulenes | Zendy

Payne Alan D. | Zendy; Skelton Brian W. | Zendy; White Allan H. | Zendy; Wege Dieter | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis, Chemistry and Structure of Some 1,1‐Dimethylcyclopropazulenes

Author(s) -

Payne Alan D.,

Skelton Brian W.,

White Allan H.,

Wege Dieter

Publication year - 2016

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201601168

Subject(s) - azulene , chemistry , electrophilic substitution , cyclopropane , electrophilic aromatic substitution , thiophene , electrophile , ring (chemistry) , stereochemistry , medicinal chemistry , computational chemistry , organic chemistry , catalysis

1,1‐Dimethylcycloprop[ e ]azulene and 1,1‐dimethylcycloprop[ f ]azulene derivatives were prepared through a short synthesis from thiophene‐1,1‐dioxides using a Houk‐Leaver azulene synthesis. The strain caused by the fusion of the cyclopropane ring had no effect on electrophilic aromatic substitution reactions. X‐ray structures of these compounds showed that cycloprop[ e ]azulenes have no or very small strain induced bond localisation, whereas cycloprop[ f ]azulene shows some minor localisation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research