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Biocompatible Glutathione Capped Functionalized Carbon Dots as Nanosensors for the Detection of Silver Nanoparticles in Aqueous Solution and Human Cells as well as Bacterial Cells
Author(s) -
Kong Lingcan,
Lu Keyu,
Ling Xia,
Zhu Pengfei,
Liu Wenwei,
Guan Hongxia,
Wang Chuanxi
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201601011
Subject(s) - luminescence , x ray photoelectron spectroscopy , detection limit , photoluminescence , fourier transform infrared spectroscopy , aqueous solution , nanosensor , nanomaterials , materials science , nanoparticle , silver nanoparticle , transmission electron microscopy , carbon fibers , analytical chemistry (journal) , chemical engineering , nanotechnology , nuclear chemistry , chemistry , optoelectronics , chromatography , organic chemistry , composite number , engineering , composite material
Functional carbon materials have aroused much attention owing to their applications in cellular imaging and sensing. In this paper, we use a hydrothermal approach to prepare luminescent sodium citrate carbon dots (CDs) using glutathione (GSH) as the surface capping reagent. The effects of feed ratio, reaction temperature and reaction time on the luminescent behavior of CDs are investigated. Subsequently, as‐prepared CDs are characterized by UV‐vis, photoluminescence, X‐ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and transmission electron microscope (TEM). The luminescent CDs exhibit good stability in the presence of various ions or photo irradiation. Furthermore, the luminescence of the CDs is reversible upon the pH cycling between pH=4 and 6. In addition, the emission intensity of CDs decreases gradually with increasing the concentration of silver nanoparticles (AgNPs) and a linear relationship between the logarithm of emission intensity and the concentration of AgNPs is observed within the investigated concentration ranging from 0 to 40 μmol•L−1. The detection limit is 0.9 μmol•L−1 in terms of signal‐to‐noise ratio of 3. More importantly, the sensor can be successfully applied to the detection of AgNPs in real lake water, urine of human, Hep‐2 cells, E. Coli and Salmonella bacteria, which offers a promising platform for environmental and biological sensing applications.