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Triazine‐Triazole Conjugates as Potent Ligands for Cu–Catalyzed Sonogashira Reaction
Author(s) -
Wang Zhenhua,
Wang Xiu,
Sun Huaming,
Zhu Zhuangli,
Zhang Guofang,
Zhang Weiqiang,
Gao Ziwei
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201600113
Subject(s) - sonogashira coupling , triazine , conjugate , combinatorial chemistry , chemistry , triazole , steric effects , ligand (biochemistry) , catalysis , click chemistry , stereochemistry , organic chemistry , palladium , receptor , biochemistry , mathematical analysis , mathematics
Triazine Triazole conjugates ( TT ) were developed as efficient ligand system for CuSO 4 ⋅5H 2 O catalyzed Sonogashira and decarboxylative cross‐coupling reaction. This new protocol showed good compatibility with a broad range of substitutents and afforded moderate to excellent yields. TT ligands are rapid constructed and highly modular electronically and sterically.